Injectable Lipolysis

The results of injectable lipolysis can be visible within a few weeks and can last permanently, provided that the patient does not gain weight.

A healthy diet and an active lifestyle must be maintained.

The number of sessions required will depend on the amount of fat to be dissolved and individual goals.

Usually, 1-3 sessions are required, at 2-week intervals.

Lipolytic agents

Wondering what's hidden in those tiny syringes that promise to transform your figure?

1. Deoxycholic Acid:

• Derived from bile acids produced by the liver.
• Action: Destroys fat cell membranes.
• Effectiveness: FDA approved for the reduction of submental fat.

Did you know that?

Deoxycholic acid is naturally present in our bodies, helping to digest fats!

2. Phosphatidylcholine: The Body's Ally

• Natural compound derived from soy.
• Action: Emulsifies fats, facilitating their elimination.
• Versatility: Used for various areas of the body.

3. Other Substances

• L-carnitine: Stimulates fat metabolism.
• Caffeine: Improves circulation and accelerates lipolysis.
• Herbal extracts: Provides synergistic effects for optimal results.

4. Safety and Regulations: Our Priority

• Strict regulations for the production and administration of substances.
• Procedures performed only by dermatologists.
• Constant monitoring of safety and efficacy.

The cost of injection lipolysis therapy will vary depending on the area treated and the number of sessions required. See the price list here

• At the Skina clinic you will benefit from injectable lipolysis with the highest quality lipolytic agents. 
• Personalised techniques to give you optimal results.
• Dedicated, experienced dermatologists.
• Patients satisfied with the results, 5***** reviews.

Asking yourself where can injectable lipolysis work wonders?

Let's explore together the areas where this aesthetic therapy can bring spectacular transformations!

Goodbye Double Chin: Reducing Submental Fat

Area: Under the chin.

• BENEFITS:
• More defined facial contour.
• Younger and slimmer appearance.
• Effectiveness: Visible results after 1-3 sessions.

Did you know that?

The submental treatment is the first FDA-approved injectable lipolysis treatment!

Dream Abdomen: Contouring and Definition

Target areas:

• Belly.
• Waist.
• "Muffin top".

Advantages:

• Slimmer silhouette.
• Better fit in clothes.
• Number of sessions: 3-6, depending on the area treated.

Enviable Legs: Thighs and Buttocks

Problem areas:

• The inner and outer thighs.
• Buttock area.

Result:

• More harmonious contour.
• Cellulite reduction.
• Recovery time: Minimal, you can return to daily activities immediately.

Toned Arms and Other Areas

• Arms (especially the triceps area).
• Back.
• Knee.

Unexpected benefits:

• Improving posture.
• Increased self-confidence.

• Treatments can be customized and combined for optimal results.
• The initial medical examination is crucial for establishing the treatment plan.

Careful consideration!! Injectable lipolysis is not a solution for weight loss, but for body contouring and definition.

Now that you've discovered the areas where injectable lipolysis can work wonders, are you ready to transform your body? Imagine what it would be like to look in the mirror and see exactly the figure you've always wanted!

• Natural and harmonious results.
• Minimally invasive procedure.
• Quick recovery.

Don't let stubborn fat get in your way! Schedule an appointment for medical examination today and take the first step towards your dream body.

Injectable lipolysis is waiting for you to sculpt your perfect figure!

STUDY:

"Efficacy of a Novel Injection Lipolysis to Induce Targeted Adipocyte Apoptosis: A Randomized, Phase IIa Study of CBL-514 Injection on Abdominal Subcutaneous Fat Reduction"

Short presentation: The study evaluates the efficacy of CBL-514, a novel injectable lipolysis agent, in inducing adipocyte apoptosis to reduce abdominal subcutaneous fat.

Key points:

• • • Promising clinical results: CBL-514 demonstrated a significant reduction in abdominal fat compared to placebo.
    • Large surface applications: Can be used on large body areas, providing flexibility in treatment.
    • Minimally invasive: The procedure is a minimally invasive alternative to surgical fat reduction methods.
  • Year of publication: 2022
  • Link to the original source: NCBI PMC

STUDY:

"Lipolytic Agents for Submental Fat Reduction: Review"

Short presentation: This study provides a review of lipolytic agents used for submental fat reduction, analyzing their efficacy and mechanisms of action.

Key points:

• • • Agents used: Sodium deoxycholate and other substances used in submental lipolysis are discussed.
    • Mechanisms of action: Exploring how these substances induce adipocyte lysis.
    • Safety and efficacy: Evaluation of the safety profile and clinical results obtained.
  • Year of publication: 2023
  • Link to the original source: Wiley Online Library

STUDY:

"Injection Lipolysis: Mechanism, Risks & FDA Approval Insights"

Short presentation: The article provides insight into the mechanisms of injectable lipolysis, associated risks, and information about FDA approvals related to this procedure.

Key points:

• • • The mechanism of injectable lipolysis: The injected substances break down fat cells, facilitating their elimination.
    • Potential risks: Discussing possible adverse effects and how to manage them.
    • FDA regulations: Information on approved substances and their use according to official guidelines.
  • Year of publication: 2020
  • Link to the original source: New York Liposuction

STUDY:

Injection Lipolysis: A Systematic Review of Literature and Our Experience with a Combination of Phosphatidylcholine and Deoxycholate over a Period of 14 Years in 1269 Patients

• Year of publication: 2018
• Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371720/
• Short presentation: This retrospective study reviews the experience of 14 years of injectable lipolysis treatment using a combination of phosphatidylcholine (PC) and deoxycholate (DC) in 1269 patients from India and Southeast Asia. The efficacy and safety of this combination in reducing localized fat in different areas of the body were evaluated.
• Key points:
  • The treatment consisted of an average of four sessions, at four-week intervals.
  • The results were evaluated 8 weeks after the last session.
  • The most notable effects were observed in the facial areas (cheeks, jawline and submental area).
  • Injectable lipolysis has been proven to be an effective and safe option for non-surgical body contouring.

STUDY:

Clinical Safety Data and Standards of Practice for Injection Lipolysis

• Year of publication: 2006
• Link: https://academic.oup.com/asj/article/26/5/575/214149
• Short presentation: The study collected clinical safety data from 75 physicians in 17 countries who performed injection lipolysis on 17,376 patients, totaling 56,320 injection sessions. The aim was to assess the safety and standard practices in injection lipolysis.
• Key points:
  • The best indication is to treat small areas of localized fat.
  • Contraindications: pregnancy, breastfeeding, age under 18 years, severe acute or chronic diseases, immunocompromised status, anticoagulant therapy.
  • The procedure was well tolerated, with minimal and temporary adverse effects.

STUDY:

Efficacy of a Novel Injection Lipolysis to Induce Targeted Adipocyte Cell Death

• Year of publication: 2022
• Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9384315/
• Short presentation: The study investigates the efficacy of a novel injectable lipolysis agent in inducing targeted fat cell death, providing a minimally invasive alternative for localized fat reduction.
• Key points:
  • The use of deoxycholic acid (DCA) as an adipocytolytic agent.
  • The procedure can be customized depending on the level and area of fat accumulation.
  • DCA mainly affects fat cells, with minimal effects on surrounding tissues.

STUDY:

The Efficacy of High-Frequency Ultrasound-Guided Injection Lipolysis in the Treatment of Localized Knee Fat Pads

• Year of publication: 2021
• Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830143/
• Short presentation: The study evaluates the effectiveness of high-frequency ultrasound-guided injectable lipolysis in the treatment of localized fat deposits in the knees.
• Key points:
  • The study included women between the ages of 26 and 55.
  • Each patient received bilateral treatment, with 14 fat areas being evaluated.
  • A significant reduction in the thickness of the fat layer at the knees was observed.
  • The ultrasound-guided technique allows for precise and effective injection.

STUDY:

Injection Lipolysis for Body Contouring

• Year of publication: 2010
• Link: https://link.springer.com/chapter/10.1007/978-3-642-02639-3_6
• Short presentation: The chapter addresses the use of injectable lipolysis for body contouring, providing information on dosages, techniques, and expected results in different areas of the body.
• Key points:
  • Recommended doses vary depending on the area treated (e.g. neck, under the chin).
  • The importance of correct injection technique for maximum effectiveness.
  • Suitable for areas with small fat deposits.

STUDY:

Clinical Safety Data and Standards of Practice for Injection Lipolysis

• Year of publication: 2009
• Link: https://pubmed.ncbi.nlm.nih.gov/19338944/
• Short presentation: The study presents safety data and practice standards for injectable lipolysis, analyzing treatments performed on 17,376 patients in 17 countries.
• Key points:
  • Evaluation of indications and contraindications for treatment.
  • The procedure had low rates of major complications.
  • The need for standardization to ensure patient safety.

STUDY:

"Fat Busters: Lipolysis for Face and Neck"

• Year of publication: 2018
• Presentation: The article discusses the use of injectable lipolysis for reducing fat in the face and neck area, offering a non-surgical alternative to liposuction.
• Key points:
  • Injectable lipolysis is effective in reducing submental fat.
  • The use of phosphatidylcholine and deoxycholate as lipolytic agents.
  • The procedure has a good safety profile and minimal recovery time.
• Link: Access the original article.

Conclusion. 

These studies demonstrate that injectable lipolysis is effective in reducing localized fat in areas such as the face (cheeks, jawline, submental area), arms, abdomen, back, thighs, knees, and calves.

The treatment is particularly indicated for areas with small to moderate fat deposits and offers a minimally invasive alternative to surgical liposuction.

It is essential that treatment is carried out by doctors, respecting safety standards and contraindications.